Bumetanide Impurity 16 - Names and Identifiers
Bumetanide Impurity 16 - Physico-chemical Properties
Molecular Formula | C7H4ClNO7S
|
Molar Mass | 281.63 |
Density | 1.896 |
Storage Condition | Room Temprature |
Bumetanide Impurity 16 - Introduction
4-chloro -3-nitro -5-sulfonic acid benzoic acid, also known as 2-nitro -4-chlorobenzenesulfonic acid, molecular formula C7H4ClNO6S.
Nature:
4-Chloro-3-nitro-5-sulfonic acid benzoic acid is a colorless to pale yellow crystal, soluble in organic solvents such as ethanol and methanol, insoluble in water. It is a strong acid.
Use:
4-Chloro-3-nitro-5-sulfonic acid benzoic acid is mainly used as a catalyst in organic synthesis reactions. It can be used to prepare various chemicals, such as pharmaceutical intermediates, dyes and photoresist, etc.
Preparation Method:
Generally, 4-chloro-3-nitro-5-sulfonic acid benzoic acid is obtained by nitrating p-nitrobenzoic acid. First, nitrobenzoic acid was nitrated in a mixed acid system of nitric acid and sulfuric acid at low temperature and concentrated nitric acid. Then, the reaction mixture is purified by extraction and crystallization to obtain the target product.
Safety Information:
4-Chloro-3-nitro-5-sulfonic acid benzoic acid is a corrosive substance, which is irritating and damaging. Wear appropriate protective gloves, goggles and face shields to avoid inhalation or contact with skin during use and handling. At the same time, it should be operated in a well-ventilated environment, and care should be taken to avoid contact with combustibles and oxidants. If exposed or inhaled, rinse immediately with plenty of water and seek medical attention.
Last Update:2024-04-09 21:11:58